THE DISTRIBUTION OF FIXED RADIOACTIVE CARBON IN GLUCOSE FROM RAT LIVER GLYCOGEN
نویسندگان
چکیده
منابع مشابه
Distribution of radioactive carbon dioxide incorporated into rat liver glycogen.
It has been demonstrated that Cl402 administered to fasted rats (2) or incubated with liver slices from fasted animals (3) yields glycogen which is labeled predominantly in carbon atoms 3 and 4. These findings are consistent with the interpretation that CO2 incorporation into glycogen proceeds by a reversal of the anaerobic glycolytic pathway (4). However, during the past several years it has b...
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The process of glycogen formation in the liver of fasted rats fed lactate has previously been found to involve at least one step in which completely oxidized, or (+4), carbon is incorporated into the 6-carbon glucose chains of the glycogen molecule (1). This incorporation occurs only under circumstances in which glycogen is accumulating. The mechanism of the incorporation is still unknown. Ther...
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An increase in the perfusate glucose concentration from near zero to about 11 mM increased glycogen synthesis in the perfused, isolated rat liver from zero to a value about half the maximum seen in the intact animal. Increased synthesis appeard to due not only to provision of substrate but also to conversion of glycogen synthetase to the active form and of glycogen phosphorylase to the inactive...
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Arey, L. B. 8; Covode, W. &I. (1943). Anat. Rec. 86, 75. Bourne, G. (1944). Lancet, 246, 688. Buschke, W., Friedenwdd, J. S . & Fleischmann, W. (1943). Johns Hopk. Hosp. Bull. 73, 143. Campbell, F. W. ti hlichaelson, I. C. (1949). Brit. J. Ophthal. 33, 248. Galloway, N. M., Carry, R. C. & Hitchin, A. D. (1948-9). Brit. J. Nutn't. 2, 228. Hartwell, S. LV. (1929). Arch. Surg., Chicago, 19, 83 j. ...
متن کاملHomogeneous glycogen synthetase b from rat liver.
Glycogen synthetase b has been purified about 2,000-fold from a crude extract of rat liver. The purification procedure consisted of the separation of the glycogen pellet by centrifugation, solubilization of the synthetase by phosphorolysis of the glycogen by endogenous phosphorylase, and adsorption and elution from Ca3(P04)2 gel. The final material appears homogeneous on gel electrophoresis. A ...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1949
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)57010-1